Aldolase C antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID : 9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 14,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be reg µLated in brain tumor, hepatomas, and lung cancer(PMID : 21548097).
Immunogen : aldolase C, fructose-bisphosphate
Aliases : ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C
Observed MW : 39 kDa
Uniprot ID : P09972
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IF
Recommended dilution : WB : 1 : 500-1 : 5000; IF : 1 : 10-1 : 100
Gene ID : 230
Research Area : Metabolism