AlaRS antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : AARS(alanyl-tRNA synthetase) is also named as AlaRS(alanine tRNA ligase 1 cytoplasmic), renal carcinoma antigen NY-REN-42 and belongs to the class-II aminoacyl-tRNA synthetase family. It can interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. AARS consists of three domains : the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stim µLating deacylation of misacylated tRNAs(PMID : 19661429).
Immunogen : alanyl-tRNA synthetase
Aliases : AARS, Alanine tRNA ligase, alanyl tRNA synthetase, AlaRS
Observed MW : 107 kDa
Uniprot ID : P49588
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF, IP
Recommended dilution : WB : 1 : 200-1 : 1000; IHC : 1 : 20-1 : 200; IF : 1 : 20-1 : 200; IP : 1 : 200-1 : 2000
Gene ID :
Research Area : Neuroscience, Metabolism