AKTIP antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background : The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conj µgating enzymes but lacks the conserved cysteine residue that enables those enzymes to conj µgate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and mod µLates PKB activity by enhancing the phosphorylation of PKB's reg µLatory sites. Alternative splicing res µLts in two transcript variants encoding the same protein.
Immunogen : AKT interacting protein
Aliases : AKT interacting protein, AKTIP, FT1 FTS, Fused toes protein homolog
Observed MW : 36 kDa
Uniprot ID : Q9H8T0
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 50 - 1 : 200
Gene ID : 64400
Research Area : Metabolism