ACVRL1 antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important reg µLator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional reg µLators. May bind activin as well.
Immunogen : activin A receptor type II-like 1
Aliases : Activin receptor like kinase 1 ACVRL1 ACVRLK1 ALK 1 ALK1 HHT, HHT2, ORW2, SKR3, TSR I
Observed MW : 56 kDa
Uniprot ID : P37023
Reactivity : Human
Application : ELISA, WB, IHC, FC, IP
Recommended dilution : WB : 1 : 200-1 : 1000; IHC : 1 : 100-1 : 400; IP : 1 : 200-1 : 1000
Gene ID : 94
Research Area : Cardiovasc µLar, Metabolism, Signal Transduction