AFF4 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : AFF4 antibody; AF5Q31 antibody; MCEF antibody; HSPC092 antibody; AF4/FMR2 family member 4 antibody; ALL1-fused gene from chromosome 5q31 protein antibody; Protein AF-5q31 antibody; Major CDK9 elongation factor-associated protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UHB7
Immunogen : Recombinant Human AF4/FMR2 family member 4 protein (77-334AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at m µLtiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors thro µgh direct interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stim µLate viral gene expression.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AFF4
Research Areas : Epigenetics and Nuclear Signaling; Cell biology