ACMSD Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : 2 amino 3 carboxymuconate 6 semialdehyde decarboxylase antibody; 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase antibody; acmsd antibody; ACMSD_HUMAN antibody; Aminocarboxymuconate semialdehyde decarboxylase antibody; Picolinate carboxylase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TDX5
Immunogen : Recombinant Human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase protein (33-129AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD µLtimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ACMSD
Research Areas : Others