ADGRG1 Antibody
Volume : 50 µg
Clone Number :
Aliases : 7 transmembrane protein with no EGF like N terminal domains 1 antibody; BFPP antibody; DKFZp781L1398 antibody; EGF TM7 like antibody; G protein coupled receptor 56 antibody; G-protein coupled receptor 56 antibody; GPR 56 antibody; Gpr56 antibody; GPR56_HUMAN antibody; Polymicrogyria bilateral frontoparietal antibody; Protein TM7XN1 antibody; TM7LN4 antibody; TM7XN1 antibody; TM7XN1 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y653
Immunogen : Recombinant Human Adhesion G-protein coupled receptor G1 protein (26-216AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, IHC, IF; Recommended dilution : IHC : 1 : 200-1 : 500, IF : 1 : 50-1 : 200
Background : Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in reg µLation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity). Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed : 22238662). Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity). Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis thro µgh a signaling pathway mediated by PRKCA (PubMed : 16757564, PubMed : 21724588). Plays an essential role in testis development (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ADGRG1
Research Areas : Neuroscience; Signal transduction