AIMP1 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : AIMP 1 antibody; Aimp1 antibody; AIMP1/p43 antibody; AIMP1_HUMAN antibody; Aminoacyl tRNA synthetase complex-interacting m µLtifunctional protein 1 antibody; ARS interacting m µLtifunctional protein 1 antibody; EMAP 2 antibody; EMAP-2 antibody; EMAP-II antibody; EMAP2 antibody; EMAPII antibody; Endothelial monocyte activating polypeptide 2 antibody; Endothelial monocyte activating polypeptide antibody; Endothelial monocyte-activating polypeptide 2 antibody; Endothelial monocyte-activating polypeptide II antibody; HLD3 antibody; M µLtisynthase complex auxiliary component p43 antibody; M µLtisynthetase complex auxiliary component p43 antibody; OTTHUMP00000219673 antibody; p43 antibody; Scye 1 antibody; Scye1 antibody; Scye1 formerly antibody; Small inducible cytokine subfamily E member 1 antibody; Small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) antibody; Small inducible cytokine subfamily E, member 1 formerly antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q12904
Immunogen : Recombinant Human Aminoacyl tRNA synthase complex-interacting m µLtifunctional protein 1 protein (25-180AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Non-catalytic component of the m µLtisynthase complex. Stim µLates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively reg µLates TGF-beta signaling thro µgh stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis thro µgh induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Reg µLates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic retic µLum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Mod µLates endothelial cell responses by degrading HIF-1A thro µgh interaction with PSMA7.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AIMP1
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cardiovasc µLar; Cell biology; Tags & Cell Markers; Immunology