AC1 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : AC1 antibody; AL1 antibody; Replication-associated protein antibody; Rep antibody; EC 2.7.7.- antibody; EC 3.1.21.- antibody; 40.4 kDa protein antibody; Protein AC1 antibody; Protein AL1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : African cassava mosaic virus (isolate West Kenyan 844) (ACMV) (Cassava latent virus (isolate West Kenyan 844))
UniProt ID : P14982
Immunogen : Recombinant African cassava mosaic virus Replication-associated protein (1-358AA)
Raised in : Rabbit
Species Reactivity : African cassava mosaic virus
Tested Applications : ELISA
Background : Essential for the replication of viral ssDNA. The closed circ µLar ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific region at the genome origin of replication. It introduces an endonucleolytic nick within the conserved sequence 5\'-TAATATTAC-3\' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5\'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3\'-OH that serves as a primer for the cell µLar DNA polymerase. The polymerase syntheVolumes the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circ µLar single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AC1
Research Areas : Others