AFG3L2 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : AFG3 (ATPase family gene 3; yeast) like 2 antibody; AFG3 ATPase family gene 3 like 2 (yeast) antibody; AFG3 ATPase family gene 3 like 2 antibody; AFG3 like protein 2 antibody; AFG3-like protein 2 antibody; AFG32_HUMAN antibody; AFG3L2 antibody; ATPase family gene 3 like 2 antibody; ATPase family gene 3 yeast antibody; EC 3.4.24.- antibody; FLJ25993 antibody; Paraplegin like protein antibody; Paraplegin-like protein antibody; SCA28 antibody; Spinocerebellar ataxia 28 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y4W6
Immunogen : Recombinant Human AFG3-like protein 2 protein (550-759AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed : 27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AFG3L2
Research Areas : Neuroscience; Cancer; Cell biology; Metabolism; Signal transduction