ADAM15 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : A disintegrin and metalloproteinase domain 15 (metargidin) antibody; A disintegrin and metalloproteinase domain 15 antibody; ADA15_HUMAN antibody; ADAM 15 antibody; ADAM metallopeptidase domain 15 antibody; Adam15 antibody; and cysteine-rich protein 15 antibody; Disintegrin and metalloproteinase domain-containing protein 15 antibody; disintegrin-like antibody; EC 3.4.24. antibody; MDC 15 antibody; MDC-15 antibody; MDC15 antibody; Metalloprotease RGD disintegrin protein antibody; Metalloproteinase like disintegrin like and cysteine rich protein 15 antibody; Metalloproteinase-like antibody; Metargidin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13444
Immunogen : Recombinant Human Disintegrin and metalloproteinase domain-containing protein 15 protein (207-452AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomer µLar cell migration. Plays a role in pathological neovasc µLarization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding thro µgh its disintegrin domain.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ADAM15
Research Areas : Cancer; Cell biology; Signal transduction