MASP1 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : MASP1 antibody; CRARF antibody; CRARF1 antibody; PRSS5Mannan-binding lectin serine protease 1 antibody; EC 3.4.21.- antibody; Complement factor MASP-3 antibody; Complement-activating component of Ra-reactive factor antibody; Mannose-binding lectin-associated serine protease 1 antibody; MASP-1 antibody; Mannose-binding protein-associated serine protease antibody; Ra-reactive factor serine protease p100 antibody; RaRF antibody; Serine protease 5) [Cleaved into : Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P48740
Immunogen : Recombinant Human Mannan-binding lectin serine protease 1 protein (20-699AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens thro µgh patterns of s µgar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to s µgar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MASP1
Research Areas : Immunology