AHRR Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : AHH antibody; AhR repressor antibody; AhRR antibody; AHRR_HUMAN antibody; aryl hydrocarbon hydroxylase reg µLator antibody; aryl hydrocarbon receptor reg µLator antibody; Aryl hydrocarbon receptor repressor antibody; Arylhydrocarbon receptor repressor antibody; bHLHe77 antibody; Class E basic helix-loop-helix protein 77 antibody; Dioxin receptor repressor antibody; KIAA1234 antibody; MGC167813 antibody; MGC176630 antibody; OTTHUMP00000221488 antibody; OTTHUMP00000221489 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : A9YTQ3
Immunogen : Recombinant Human Aryl hydrocarbon receptor repressor protein (255-506AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Mediates dioxin toxicity and is involved in reg µLation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter reg µLatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoreg µLates its expression by associating with its own XRE site.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AHRR
Research Areas : Epigenetics and Nuclear Signaling