AHR Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Ah receptor antibody; AhR antibody; AHR_HUMAN antibody; Aromatic hydrocarbon receptor antibody; Aryl hydrocarbon receptor antibody; Aryl hydrocarbon receptor precursor antibody; bHLHe76 antibody; Class E basic helix loop helix protein 76 antibody; Class E basic helix-loop-helix protein 76 antibody; HGNC : 348 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35869
Immunogen : Recombinant Human Aryl hydrocarbon receptor protein (126-353AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of m µLtiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle reg µLation. Likely to play an important role in the development and maturation of many tissues. Reg µLates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AHR
Research Areas : Epigenetics and Nuclear Signaling