ADCY6 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : AC6 antibody; ACVI antibody; ADCY 6 antibody; Adcy6 antibody; ADCY6_HUMAN antibody; ADCYB antibody; Adenylate cyclase 6 antibody; Adenylate cyclase type 6 antibody; Adenylate cyclase type VI antibody; Adenylyl cyclase 6 antibody; ATP pyrophosphate lyase 6 antibody; ATP pyrophosphate-lyase 6 antibody; Ca(2+) inhibitable adenylyl cyclase antibody; Ca(2+)-inhibitable adenylyl cyclase antibody; DKFZp779F075 antibody; EC 4.6.1.1 antibody; KIAA0422 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43306
Immunogen : Recombinant Human Adenylate cyclase type 6 protein (9-118AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes the formation of the signaling molec µLe cAMP downstream of G protein-coupled receptors (PubMed : 17916776, PubMed : 17110384). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vasc µLar smooth muscle cells (PubMed : 17916776). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in reg µLating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the reg µLation of pancreatic amylase and fluid secretion (By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA. This promotes increased phosphorylation of various proteins, including AKT. Plays a role in reg µLating cardiac sarcoplasmic retic µLum Ca(2+) uptake and storage, and is required for normal heart ventric µLar contractibility. May contribute to normal heart function (By similarity). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol (PubMed : 17916776). Contributes to bone cell responses to mechanical stim µLi (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ADCY6
Research Areas : Neuroscience; Cancer; Metabolism; Signal transduction